Use of Alloplastic Meshes in Abdominal Wounds of Rats with Induced Peritonitis

BACKGROUND The use of alloplastic meshes has been historically contra-indicated in patients with infection. AIM To evaluate the use of polypropylene meshes in the treatment of abdominal wall defects in rats with peritonitis. METHODS Twenty Wistar female rats were divided into two groups: induction of peritonitis (test group) and without peritonitis (control group). An abdominal wall defect was created in all animals, and polypropylene mesh was applied. The evaluation of the tensile strength of the mesh was carried out using tensiometer and microscopic analysis of the healing area was done. RESULTS More adhesion of the mesh to the rat abdominal wall was observed in test group. The histopathological analyses showed prevalence of moderate to accentuated granulation tissue in both groups, without significant differences. CONCLUSION The use of the mesh coverage on abdominal wall defects of rats with induced peritonitis did not show worse results than its use in healthy animals, nor was its integration to the resident tissue any worse.